Not medical advice

Supplement Hype reports the state of evidence and grades claims. It is not a substitute for a doctor or pharmacist and does not diagnose, treat, or cure anything. Read the full disclaimer →

Head to head

CoQ10 (ubiquinone/ubiquinol) vs Vitamin K2 (MK-7)

On the strength of human evidence, CoQ10 (ubiquinone/ubiquinol) comes out ahead (evidence 45 vs 35). But they're often used for different things — read each claim before deciding.

Shared goals: Heart

CoQ10 (ubiquinone/ubiquinol)

Limited

best case is for statin users and heart failure

Marketed
Evidence
Overhyped

Marketing intensity 70 of 100. Evidence strength 45 of 100. Verdict: Overhyped.

A reasonable add-on for statin muscle aches and heart failure, where the evidence is mixed-to-promising. As a general 'energy and anti-aging' pill for healthy people, it's weak.

Full evidence on CoQ10 (ubiquinone/ubiquinol) →

Vitamin K2 (MK-7)

▲ Trending

the calcium-traffic-cop, on surrogate evidence

Marketed
Evidence
Overhyped

Marketing intensity 70 of 100. Evidence strength 35 of 100. Verdict: Overhyped.

A plausible idea - help calcium land in bone, not arteries - with promising biomarker and imaging data. But hard clinical proof (fewer fractures, fewer heart attacks) isn't there yet.

Full evidence on Vitamin K2 (MK-7) →

Side by side

Metric CoQ10 (ubiquinone/ubiquinol) Vitamin K2 (MK-7)
Overall tier Limited Limited
Evidence score 45/100 35/100
Hype score 70/100 70/100
Verdict Overhyped Overhyped
Safety concern low low

Quick answers

CoQ10 (ubiquinone/ubiquinol) or Vitamin K2 (MK-7) — which has better evidence?

On the strength of human evidence, CoQ10 (ubiquinone/ubiquinol) comes out ahead (evidence 45 vs 35). But they're often used for different things — read each claim before deciding.

Can you take CoQ10 (ubiquinone/ubiquinol) and Vitamin K2 (MK-7) together?

This page compares the evidence, not interactions. Some supplements interact with each other or with medications — check each one's safety section and talk to a pharmacist before stacking.