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Search a supplement and see how strong the human evidence actually is for
each thing it claims, and how far the marketing has run ahead of the
science. Graded claim by claim. Sources on every grade.
54 supplements·4 actually backed by strong evidence·0 grades for sale
A century-old medical dye with interesting mechanisms, almost no long-term human evidence for the biohacker claims, and real, specific dangers if you take antidepressants.
Marketed
95
Evidence
20
Severely overhyped
Marketing intensity 95 of 100. Evidence strength 20 of 100.
Verdict: Severely overhyped.
A Himalayan resin with a couple of tiny testosterone studies and a big TikTok budget. The heavy-metal contamination risk is the part the videos never mention.
Marketed
85
Evidence
20
Severely overhyped
Marketing intensity 85 of 100. Evidence strength 20 of 100.
Verdict: Severely overhyped.
It reliably raises NAD+ in your blood. Whether that does anything for human aging is unproven - and in the US the FDA no longer allows it to be sold as a supplement.
Marketed
90
Evidence
30
Severely overhyped
Marketing intensity 90 of 100. Evidence strength 30 of 100.
Verdict: Severely overhyped.
A genuinely interesting 'senolytic' flavonoid that extended lifespan in mice and is now in human trials. But there are no human longevity results yet, and absorption is poor.
Marketed
78
Evidence
20
Severely overhyped
Marketing intensity 78 of 100. Evidence strength 20 of 100.
Verdict: Severely overhyped.
The molecule that launched the longevity-supplement craze - on yeast and worms. In humans it's barely absorbed and the lifespan and heart claims haven't held up.
Marketed
80
Evidence
25
Severely overhyped
Marketing intensity 80 of 100. Evidence strength 25 of 100.
Verdict: Severely overhyped.
A pricey powdered multivitamin with great marketing. The handful of trials are mostly run by the makers, and none show it does what the podcast ads imply.
Marketed
88
Evidence
35
Severely overhyped
Marketing intensity 88 of 100. Evidence strength 35 of 100.
Verdict: Severely overhyped.
Helps hair and nails only if you're genuinely deficient - which is rare. For everyone else it's a placebo with a real side effect: it can throw off lab results.
Marketed
78
Evidence
28
Severely overhyped
Marketing intensity 78 of 100. Evidence strength 28 of 100.
Verdict: Severely overhyped.
A compelling longevity mechanism (it triggers autophagy) with encouraging animal data - but the human cognition trials are small and mixed, not the proven memory aid it's sold as.
Marketed
72
Evidence
25
Severely overhyped
Marketing intensity 72 of 100. Evidence strength 25 of 100.
Verdict: Severely overhyped.
A gym-bag staple that the science has largely passed by. If you hit your protein target, BCAAs add little - whole protein already contains them, plus the other amino acids you need.
Marketed
75
Evidence
30
Severely overhyped
Marketing intensity 75 of 100. Evidence strength 30 of 100.
Verdict: Severely overhyped.
A staple of fat-burner blends with barely-there weight-loss data - and a real, dose-dependent risk of liver injury, especially in the exact 'pill-plus-diet' scenario it's sold for.
Marketed
75
Evidence
30
Severely overhyped
Marketing intensity 75 of 100. Evidence strength 30 of 100.
Verdict: Severely overhyped.
Marketed as the magnesium that reaches your brain. The human evidence is one or two small, industry-funded trials - promising, nowhere near proven, and priced at a steep premium.
Marketed
80
Evidence
35
Severely overhyped
Marketing intensity 80 of 100. Evidence strength 35 of 100.
Verdict: Severely overhyped.
A genuinely interesting mushroom with promising animal data and a few small, mixed human trials. The 'grow new brain cells' marketing is far ahead of what's been shown in people.
Marketed
80
Evidence
40
Overhyped
Marketing intensity 80 of 100. Evidence strength 40 of 100.
Verdict: Overhyped.
Real metabolic effects, genuinely studied - but the viral 'nature's Ozempic' label is marketing fiction, and the drug interactions are the part TikTok skips.
Marketed
88
Evidence
50
Overhyped
Marketing intensity 88 of 100. Evidence strength 50 of 100.
Verdict: Overhyped.
Better evidenced than most longevity supplements - real RCTs show small gains in muscle strength and mitochondrial markers. Caveats: effects are modest, trials are small and industry-funded.
Marketed
76
Evidence
38
Overhyped
Marketing intensity 76 of 100. Evidence strength 38 of 100.
Verdict: Overhyped.
Some weak signal for mood and sleep, but the studies are poor - and because it raises serotonin, mixing it with antidepressants is genuinely dangerous.
Marketed
70
Evidence
35
Overhyped
Marketing intensity 70 of 100. Evidence strength 35 of 100.
Verdict: Overhyped.
Better evidence than most wellness trends for cutting respiratory infections. The 'heals your gut and fixes everything' framing is a big leap past the data.
Marketed
80
Evidence
45
Overhyped
Marketing intensity 80 of 100. Evidence strength 45 of 100.
Verdict: Overhyped.
Sold as instant calm, but the catch is basic biology: oral GABA struggles to cross into the brain. A few small trials hint at a sleep effect anyway, by unclear means.
Marketed
70
Evidence
35
Overhyped
Marketing intensity 70 of 100. Evidence strength 35 of 100.
Verdict: Overhyped.
More real evidence than most 'test boosters' - it does nudge testosterone, mostly in men who are already low. The TikTok 'alpha' framing is way ahead of the data.
Marketed
80
Evidence
45
Overhyped
Marketing intensity 80 of 100. Evidence strength 45 of 100.
Verdict: Overhyped.
A plausible idea - help calcium land in bone, not arteries - with promising biomarker and imaging data. But hard clinical proof (fewer fractures, fewer heart attacks) isn't there yet.
Marketed
70
Evidence
35
Overhyped
Marketing intensity 70 of 100. Evidence strength 35 of 100.
Verdict: Overhyped.
A huge-selling joint supplement with surprisingly mixed data. Chondroitin may modestly help pain; glucosamine's effect is weak; and the popular combo often fails to beat placebo.
Marketed
70
Evidence
38
Overhyped
Marketing intensity 70 of 100. Evidence strength 38 of 100.
Verdict: Overhyped.
A 2023 mouse study lit up the longevity world - then a 2025 human study undercut the core premise. For exercise there's a small, real signal; for living longer, it's unproven.
Marketed
70
Evidence
40
Overhyped
Marketing intensity 70 of 100. Evidence strength 40 of 100.
Verdict: Overhyped.
A reasonable add-on for statin muscle aches and heart failure, where the evidence is mixed-to-promising. As a general 'energy and anti-aging' pill for healthy people, it's weak.
Marketed
70
Evidence
45
Overhyped
Marketing intensity 70 of 100. Evidence strength 45 of 100.
Verdict: Overhyped.
Some strains genuinely work for specific problems. The catch the marketing hides: benefits are strain-specific, so a random 'gut health' capsule usually isn't the one studied.
Marketed
80
Evidence
55
Overhyped
Marketing intensity 80 of 100. Evidence strength 55 of 100.
Verdict: Overhyped.
A well-tolerated, easily-absorbed form of magnesium with a small but real sleep signal. The 'fixes your sleep and anxiety' framing still runs ahead of the data.
Marketed
72
Evidence
50
Overhyped
Marketing intensity 72 of 100. Evidence strength 50 of 100.
Verdict: Overhyped.
Essential and genuinely energising if you're deficient. The 'B12 for energy' shots and gummies do nothing measurable if your levels are already normal.
Marketed
75
Evidence
55
Slightly overhyped
Marketing intensity 75 of 100. Evidence strength 55 of 100.
Verdict: Slightly overhyped.
Best-supported paired with caffeine for smoother focus. As a standalone anti-anxiety or sleep cure, the evidence is thinner than the nootropic marketing suggests.
Marketed
68
Evidence
50
Slightly overhyped
Marketing intensity 68 of 100. Evidence strength 50 of 100.
Verdict: Slightly overhyped.
People feel it helps them sleep, and meta-analyses pick up a subjective benefit - but it disappears on objective sleep measures, and the trials are messy.
Marketed
58
Evidence
40
Slightly overhyped
Marketing intensity 58 of 100. Evidence strength 40 of 100.
Verdict: Slightly overhyped.
One of the better-supported nootropic herbs for memory - but it works slowly over weeks, not as an instant focus hit, and the gut side effects are real.
Marketed
62
Evidence
52
Slightly overhyped
Marketing intensity 62 of 100. Evidence strength 52 of 100.
Verdict: Slightly overhyped.
Genuinely helpful for holding cognition together under acute stress or sleep deprivation - but largely useless as an everyday 'focus' pill when you're rested.
Marketed
55
Evidence
45
Slightly overhyped
Marketing intensity 55 of 100. Evidence strength 45 of 100.
Verdict: Slightly overhyped.
Useful for an actual deficiency and possibly for shortening colds if you start lozenges fast. As an everyday testosterone or immunity booster in well-fed people, it's oversold.
Marketed
65
Evidence
55
Slightly overhyped
Marketing intensity 65 of 100. Evidence strength 55 of 100.
Verdict: Slightly overhyped.
Genuinely fixes fatigue when you're iron-deficient. But taking it without a blood test is a real mistake - excess iron is harmful and there's no easy way to get rid of it.
Marketed
60
Evidence
55
Hype ≈ evidence
Marketing intensity 60 of 100. Evidence strength 55 of 100.
Verdict: Hype ≈ evidence.
One of the better-evidenced herbal mood supports - multiple trials show a real antidepressant effect, in some studies comparable to SSRIs. The honest caveats are trial size and cost.
Marketed
60
Evidence
55
Hype ≈ evidence
Marketing intensity 60 of 100. Evidence strength 55 of 100.
Verdict: Hype ≈ evidence.
Quietly effective and under-marketed. The nitrate in beetroot genuinely lowers blood pressure a little and improves endurance - a rare case of substance over hype.
Marketed
45
Evidence
70
Better than its hype
Marketing intensity 45 of 100. Evidence strength 70 of 100.
Verdict: Better than its hype.
One of the rare supplements where the evidence beats the hype. Cheap, unglamorous, and genuinely effective for cholesterol, regularity and blood sugar.
Marketed
40
Evidence
80
Better than its hype
Marketing intensity 40 of 100. Evidence strength 80 of 100.
Verdict: Better than its hype.
The grade is set before any product is attached, and never depends on who pays.
Checkable
Every claim cites primary human research. Each page shows when it was last reviewed.
Honest both ways
We flag what's overhyped — and what's actually better than its reputation.
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How is Supplement Hype different from a 'best supplements' list?
Those lists are usually affiliate marketing — the ranking follows the commission. Here, every grade is set from the human evidence before any product is ever attached, and the grade never changes for money.
What does the Hype Gap meter actually mean?
Two bars on the same 0–100 scale: how loudly a supplement is marketed versus how strong the human evidence is for its best-supported use. The bigger the gap, the more the marketing has run ahead of the science.
Why grade each claim separately?
Because one supplement can be Strong for one use and Weak for another. Creatine is excellent for strength but unproven for cognition; omega-3 is strong for triglycerides but weak as general 'heart health' from a tiny softgel.
Is this medical advice?
No. Supplement Hype reports the state of evidence and grades claims. It is not a substitute for a doctor or pharmacist and does not diagnose, treat, or cure anything.
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