Supplement Hype reports the state of evidence and grades claims. It is not a
substitute for a doctor or pharmacist and does not diagnose, treat, or cure
anything. Read the full disclaimer →
Ranked by the strength of human evidence — not popularity. 14 entries touch this goal. Each is graded
claim by claim, because the same supplement can be strong for one use and
weak for another.
One of the better-evidenced herbal mood supports - multiple trials show a real antidepressant effect, in some studies comparable to SSRIs. The honest caveats are trial size and cost.
Marketed
60
Evidence
55
Hype ≈ evidence
Marketing intensity 60 of 100. Evidence strength 55 of 100.
Verdict: Hype ≈ evidence.
One of the better-supported nootropic herbs for memory - but it works slowly over weeks, not as an instant focus hit, and the gut side effects are real.
Marketed
62
Evidence
52
Slightly overhyped
Marketing intensity 62 of 100. Evidence strength 52 of 100.
Verdict: Slightly overhyped.
Best-supported paired with caffeine for smoother focus. As a standalone anti-anxiety or sleep cure, the evidence is thinner than the nootropic marketing suggests.
Marketed
68
Evidence
50
Slightly overhyped
Marketing intensity 68 of 100. Evidence strength 50 of 100.
Verdict: Slightly overhyped.
A well-tolerated, easily-absorbed form of magnesium with a small but real sleep signal. The 'fixes your sleep and anxiety' framing still runs ahead of the data.
Marketed
72
Evidence
50
Overhyped
Marketing intensity 72 of 100. Evidence strength 50 of 100.
Verdict: Overhyped.
Genuinely helpful for holding cognition together under acute stress or sleep deprivation - but largely useless as an everyday 'focus' pill when you're rested.
Marketed
55
Evidence
45
Slightly overhyped
Marketing intensity 55 of 100. Evidence strength 45 of 100.
Verdict: Slightly overhyped.
A genuinely interesting mushroom with promising animal data and a few small, mixed human trials. The 'grow new brain cells' marketing is far ahead of what's been shown in people.
Marketed
80
Evidence
40
Overhyped
Marketing intensity 80 of 100. Evidence strength 40 of 100.
Verdict: Overhyped.
People feel it helps them sleep, and meta-analyses pick up a subjective benefit - but it disappears on objective sleep measures, and the trials are messy.
Marketed
58
Evidence
40
Slightly overhyped
Marketing intensity 58 of 100. Evidence strength 40 of 100.
Verdict: Slightly overhyped.
Some weak signal for mood and sleep, but the studies are poor - and because it raises serotonin, mixing it with antidepressants is genuinely dangerous.
Marketed
70
Evidence
35
Overhyped
Marketing intensity 70 of 100. Evidence strength 35 of 100.
Verdict: Overhyped.
Sold as instant calm, but the catch is basic biology: oral GABA struggles to cross into the brain. A few small trials hint at a sleep effect anyway, by unclear means.
Marketed
70
Evidence
35
Overhyped
Marketing intensity 70 of 100. Evidence strength 35 of 100.
Verdict: Overhyped.
Based on human evidence, the best-supported options here are Omega-3 (EPA/DHA fish oil), Saffron, Bacopa monnieri. Each is graded claim by claim — open a card for the sources.
Which mood & stress supplements are overhyped?
Watch out for 5-HTP — the marketing runs well ahead of the human evidence for these.